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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T39481 NVP-DPP728 dihydrochloride

NVP-DPP728 dihydrochloride

NVP-DPP728 dihydrochloride is a highly potent, selective, and orally active inhibitor of dipeptidyl peptidase IV (DPP-IV), with a binding affinity (K i ) of 11 nM. This compound proves useful for investigating diabetes mellitus in research studies.
T74978 DPP IV/hCA II-IN-1

DPP IV/hCA II-IN-1 是一种有效的选择性二肽肽酶 IV (DPP IV) 和碳酸酐酶 (CA) 抑制剂,抑制 DPP IV 的 IC50值为 0.049 μM, 抑制 CA II、CA VB、CA VA、CA IX、CA I 和 CA IV 的 Ki 值分别为 0.0361、0.0428、0.0941、0.1328、0.2615 和 3.034 μM。
T21691 NVP DPP 728 dihydrochloride

NVP-DPP728 是一种有效、可逆、腈依赖性二肽基肽酶 IV (DPP-IV)抑制剂,Ki 值为 11 nM。NVP-DPP728 可抑制胰高血糖素样肽-1 (GLP-1)的降解,从而增强响应于葡萄糖摄入的胰岛素释放。NVP-DPP728 可用于糖尿病研究。

化合物

NVP-DPP728 dihydrochloride
Cat.No: T39481
Synonym: NVP-DPP728 dihydrochloride
Target:
DPP IV/hCA II-IN-1
Cat.No: T74978
Synonym:
Target:
NVP DPP 728 dihydrochloride
Cat.No: T21691
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPH-02628 Cathepsin C Protein, Mouse, Recombinant (His & Myc)

Dipeptidyl transferase,Di...

Mouse E. coli
Thiol protease. Has dipeptidylpeptidase activity. Can act as both an exopeptidase and endopeptidase. Can degrade glucagon. Plays a role in the generation of cytotoxic lymphocyte effector function.
TMPY-02070 Cystatin SN Protein, Human, Recombinant (His)

CST1,cystatin SN

Human HEK293 Cells
Cystatin-SN, also known as Cystain-SA-I, Cystatin-1, Salivary cystatin-SA-1 and CST1, is a secreted protein which belongs to thecystatin family. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. Cystatin-SN / CST1 is expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Cy...
TMPY-00732 Cathepsin C Protein, Human, Recombinant (His)

DPP-I,PLS,JP,cathepsin C,CPPI,DPP...

Human HEK293 Cells
Cathepsins are proteases found in many types of cells conserved in all animals, which have a vital role in mammalian cellular turnover such as bone resorption. The lysosomal cysteine protease Cathepsin C (CTSC), also known as dipeptidyl peptidase I (DPPI/DPP1), activates a number of granule-associated serine proteases with pro-inflammatory and immune functions by removal of their inhibitory N-terminal dipeptides. This lysosomal exo-cysteine protease belonging to the peptidase C1 family. Active c...
TMPY-06885 SARS-CoV-2 XBB.1.16 (Omicron) Spike S1+S2 trimer Protein (ECD, His)

The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPY-01027 Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His)

carnitine palmitoyltransferase 1B...

Mouse HEK293 Cells
Mast Cell Protease 1 (MMCP-1), also known as MCP-1, MCPT-1 and β-chymase, is a member of the Chymase family of chymotrypsin-like serine proteases. MCPT-1 is a 26 kDa β-chymase that is a component of mast cell granules. It is a 226 amino acid (aa) protein that has a conserved pattern of six cysteines and one potential glycosylation site. The granule-derived mouse mast cell proteases-1 and -2 (mMCP-1 and -2) colocalize in similar quantities in mucosal mast cells but micrograms of mMCP-1 compared w...

重组蛋白

Cathepsin C Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02628
Species: Mouse
Expression System: E. coli
Cystatin SN Protein, Human, Recombinant (His)
Cat.No: TMPY-02070
Species: Human
Expression System: HEK293 Cells
Cathepsin C Protein, Human, Recombinant (His)
Cat.No: TMPY-00732
Species: Human
Expression System: HEK293 Cells
SARS-CoV-2 XBB.1.16 (Omicron) Spike S1+S2 trimer Protein (ECD, His)
Cat.No: TMPY-06885
Species:
Expression System:
Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01027
Species: Mouse
Expression System: HEK293 Cells
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